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5 mg/kg to 6 adult patients with severe renal failure. 61 mcg/mL) Acyclovir is given as an infusion into a vein, usually once every 8 hours. Initial treatment: 200 mg PO q4hr while awake (5 times daily) for 10 days or 400 mg PO q8hr for 7-10 days. As the administered dose increases, the bioavailability decreases, resulting in less than dose proportional increase in acyclovir concentrations (e. Acyclovir is given as an infusion into a vein, usually once every 8 hours. [34213] In persons living with HIV, treat for 21 days. Children >40 kg Same as adult dose. Chronic suppression for recurrence: 400 mg PO q12hr for up to 12 months. Each 250 mg vial of Acyclovir IV Injection should be reconstituted by the addition of 10 ml of either Water for Injection or Sodium Chloride Intravenous Infusion (0. [34408] Use ideal body weight when dosing persons with obesity. The peak and trough plasma levels during the 47 hours preceding hemodialysis were 8. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. It is usually given over 1 hour every 8 hours. 7 mcg/mL, respectively Acyclovir injection comes as a solution to be injected intravenously (into a vein). INDICATIONS AND CLINICAL USE Acyclovir Sodium Injection is indicated for the treatment of initial and recurrent. Therapy should be HOW SUPPLIED NDC - Acyclovir for Injection, USP - Packaging - 68382-125-10 - 500 mg/vial - 10 vials packed in a carton - 68382-126-10 - 1,000 mg/vial - 10 vials packed in a carton - Vial PACKAGE LABEL - PRINCIPAL DISPLAY PANEL. This medicine must be given slowly, and the infusion can take at least 1 hour to complete Acyclovir was administered at a dose of 2. Consult DOSAGE AND ADMINISTRATION section for recommended adjustments in dosing based upon creatinine clearance. The length of treatment depends on your general health, the type of infection you have, your age, and how well you respond to the medication. Varicella-Zoster Infections Zoster in immunocompromised patients: 10 mg/kg infused at a constant rate over 1 hour, every 8 hours for 7 days. Acyclovir for Injection, USP was administered at a dose of 2. [34361] The FDA-approved dose is 20 mg/kg/dose IV every 8 hours for 10 days. Acyclovir was administered at a dose of 2. Intermittent treatment for recurrence: 200 mg PO q4hr while awake (5 times daily) for 5 days; initiate at earliest sign or symptom of recurrence. 7 mcg/mL, respectively INTRAMUSCULAR OR SUBCUTANEOUS INJECTION MUST BE AVOIDED (see WARNINGS). Consult DOSAGE AND ADMINISTRATION for recommended adjustments in dosing based upon creatinine clearance. Of acyclovir elimination, accounting for 62 to 91% of the dose administered. [34408] Infants 1 to 2 months† 20 mg/kg/dose IV every 8 hours for 21 days A maximum dose equivalent to 20 mg/kg every 8 hours should not be exceeded for any patient. Acyclovir injection comes as a solution to be injected intravenously (into a vein). 200 mg orally every 4 hours 5 times a day for 10 days (manufacturer dosing) 400 mg orally 3 times a day for 5 to 10 days (CDC recommendation) Severe Disease or Complications Requiring Hospitalization: 5 mg/kg IV every 8 hours for 5 days (manufacturer dosing). 10 mg/kg infused at a constant rate over 1 hour, every 8 hours for 10 days. Adult: 800 mg 5 times daily at approx 4-hourly intervals, omit night time dose. Dosage Herpes Simplex Infections: Mucosal and Cutaneous Herpes Simplex (HSV-1 and HSV-2) Infections in Immunocompromised Patients Adults and Adolescents (12 years of age and older) 5 mg/kg infused at a constant rate over 1 hour, every 8 hours for 7 days.. Children aged between 3 months and 12 years:. The half-life and total body clearance of acyclovir in pediatric patients over 1 year of age is similar to those in adults with normal renal function. This medicine must be given slowly, and the infusion can take at least 1 hour to complete Genital Herpes. Your doctor will tell you how long to use acyclovir injection Acyclovir for Injection, USP was administered at a dose of 2. Child: 20 mg/kg/dose 4 times daily. Acyclovir for Injection, USP is a synthetic nucleoside analogue, active against herpes viruses. Acyclovir is poorly absorbed from the GI tract, with an oral bioavailability of 10% to 20%. This provides a solution containing 25 mg Acyclovir per ml Acyclovir was administered at a dose of 2. Acyclovir for Injection, USP is a sterile lyophilized powder for intravenous administration only.

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